Heparan Sulfate Is a Cellular Receptor for Enteric Human Adenoviruses

Heparan Sulfate Is a Cellular Receptor for Enteric Human Adenoviruses

Human adenovirus (HAdV)-F40 and -F41 are leading causes of diarrhea and diarrhea-associated mortality in children under the age of five, but the mechanisms by which they infect host cells are poorly understood. HAdVs initiate infection through interactions between the knob domain of the fiber capsid...

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Bibliographic Details
Main Authors: Anandi Rajan, Elin Palm, Fredrik Trulsson, Sarah Mundigl, Miriam Becker, B. David Persson, Lars Frängsmyr, Annasara Lenman
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Viruses
Subjects:
enteric adenovirus
heparan sulfate
short fibers
capsid proteins
fiber knobs
Online Access:https://www.mdpi.com/1999-4915/13/2/298

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https://www.mdpi.com/1999-4915/13/2/298

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