Synthesis and antitumor evaluation of thiophene based azo dyes incorporating pyrazolone moiety

Synthesis and antitumor evaluation of thiophene based azo dyes incorporating pyrazolone moiety

A series of thiophene incorporating pyrazolone moieties 5a–f and 6a–c were synthesized via diazo coupling of diazonium salt of 3-substituted-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophenes 1a–c with 3-methyl-1H-pyrazol-5(4H)-one, 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one or 3-amino-1H-pyrazol-5(4H)-one, r...

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Bibliographic Details
Main Authors: Moustafa A. Gouda, Hadeer Fakhr Eldien, Margret M. Girges, Moged A. Berghot
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Journal of Saudi Chemical Society
Subjects:
Thiophene
Pyrazoles
Azo dyes
Color measurements
Fastness properties
Antitumor evaluation
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610312000804

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http://www.sciencedirect.com/science/article/pii/S1319610312000804

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