Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome

Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome

Robert syndrome (RBS) and Cornelia de Lange syndrome (CdLS) are human developmental disorders characterized by craniofacial deformities, limb malformation and mental retardation. These birth defects are collectively termed cohesinopathies as both arise from mutations in cohesion genes. CdLS arises d...

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Bibliographic Details
Main Authors: Rajeswari Banerji, Robert V. Skibbens, M. Kathryn Iovine
Format: Article
Language:English
Published: The Company of Biologists 2017-12-01
Series:Biology Open
Subjects:
Roberts Syndrome
Cornelia de Lange syndrome
Cohesin
esco2
smc3
cx43
Zebrafish
Regeneration
Transcription
Online Access:http://bio.biologists.org/content/6/12/1802

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