Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome
Robert syndrome (RBS) and Cornelia de Lange syndrome (CdLS) are human developmental disorders characterized by craniofacial deformities, limb malformation and mental retardation. These birth defects are collectively termed cohesinopathies as both arise from mutations in cohesion genes. CdLS arises d...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2017-12-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/6/12/1802 |