A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01E on blood stage immunity in young Kenyan children [version 1; peer review: 1 approved, 2 approved with reservations]

A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01E on blood stage immunity in young Kenyan children [version 1; peer review: 1 approved, 2 approved with reservations]

Background: RTS,S/AS01 E, the most advanced malaria vaccine confers partial immunity. The vaccine-induced pre-erythrocytic immunity reduces exposure to blood-stage parasites, delaying acquisition of antibodies to blood-stage antigens.  However, the duration of this effect is unknown. Methods: We mea...

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Bibliographic Details
Main Authors: Francis M. Ndungu, Jedida Mwacharo, Juliana Wambua, Patricia Njuguna, Kevin Marsh, Chris Drakeley, Philip Bejon
Format: Article
Language:English
Published: Wellcome 2019-03-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/4-42/v1

Internet

https://wellcomeopenresearch.org/articles/4-42/v1

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