Insights of Crosstalk between p53 Protein and the MKK3/MKK6/p38 MAPK Signaling Pathway in Cancer
TP53 is universally recognized as a pivotal protein in cell-cycle fate and apoptotic induction and, unsurprisingly, it is one of the most commonly hijacked control mechanisms in cancer. Recently, the kinase MKK3 emerged as a potential therapeutic target in different types of solid tumor being linked...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-05-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/10/5/131 |