A theoretical perspective of the physical properties of different RNA modifications with respect to RNA duplexes

Epitranscriptomic variations include >140 different RNA modifications, many of which can serve as disease biomarkers.Owing to the challenges on synthesizing modified RNA oligos, majority of earlier studies on the effects of RNA modifications to RNA duplexes focused on selected individual epitrans...

Full description

Bibliographic Details
Main Authors: Norman H.L. Chiu, Jennifer H. Simpson, Hongzhou Wang, Bakhos A. Tannous
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:BBA Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2667160321000247