AMPK regulates circadian rhythms in a tissue- and isoform-specific manner.
AMP protein kinase (AMPK) plays an important role in food intake and energy metabolism, which are synchronized to the light-dark cycle. In vitro, AMPK affects the circadian rhythm by regulating at least two clock components, CKIα and CRY1, via direct phosphorylation. However, it is not known whether...
Main Authors: | Jee-Hyun Um, Julie S Pendergast, Danielle A Springer, Marc Foretz, Benoit Viollet, Alexandra Brown, Myung K Kim, Shin Yamazaki, Jay H Chung |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-03-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3069094?pdf=render |
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