Phenothiazines Enhance Mild Hypothermia-induced Neuroprotection via PI3K/Akt Regulation in Experimental Stroke

Abstract Physical hypothermia has long been considered a promising neuroprotective treatment of ischemic stroke, but the treatment’s various complications along with the impractical duration and depth of therapy significantly narrow its clinical scope. In the present study, the model of reversible r...

Full description

Bibliographic Details
Main Authors: Hong An, Yunxia Duan, Di Wu, James Yip, Omar Elmadhoun, Joshua C. Wright, Wenjuan Shi, Kaiyin Liu, Xiaoduo He, Jingfei Shi, Fang Jiang, Xunming Ji, Yuchuan Ding
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06752-5