C-Jun N-terminal kinase inhibitors: Structural insight into kinase-inhibitor complexes

The activation of c-Jun N-terminal kinases (JNKs) plays an important role in physiological processes including neuronal function, immune activity, and development, and thus, JNKs have been a therapeutic target for various diseases such as neurodegenerative diseases, inflammation, and cancer. Efforts...

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Bibliographic Details
Main Authors: Men Thi Hoai Duong, Joon-Hwa Lee, Hee-Chul Ahn
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020303020