Osteopontin enhances multi-walled carbon nanotube-triggered lung fibrosis by promoting TGF-β1 activation and myofibroblast differentiation

Abstract Background Carbon nanotubes (CNTs) have been used in a variety of applications because of their unique properties and functions. However, many CNTs have been shown to induce lung fibrosis in experimental animals with some at a potency greater than that of silica, raising concern over possib...

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Bibliographic Details
Main Authors: Jie Dong, Qiang Ma
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Particle and Fibre Toxicology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12989-017-0198-0