Osteopontin enhances multi-walled carbon nanotube-triggered lung fibrosis by promoting TGF-β1 activation and myofibroblast differentiation
Abstract Background Carbon nanotubes (CNTs) have been used in a variety of applications because of their unique properties and functions. However, many CNTs have been shown to induce lung fibrosis in experimental animals with some at a potency greater than that of silica, raising concern over possib...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-06-01
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Series: | Particle and Fibre Toxicology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12989-017-0198-0 |