A robust protocol for the generation of human midbrain organoids

Summary: The lack of advanced in vitro models recapitulating the human brain complexity is still a major obstacle in brain development and neurological disease research. Here, we describe a robust protocol to derive human midbrain organoids from neuroepithelial stem cells. These complex 3D models ar...

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Bibliographic Details
Main Authors: Alise Zagare, Matthieu Gobin, Anna S. Monzel, Jens C. Schwamborn
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721002318