TOP2B: The First Thirty Years

TOP2B: The First Thirty Years

Type II DNA topoisomerases (EC 5.99.1.3) are enzymes that catalyse topological changes in DNA in an ATP dependent manner. Strand passage reactions involve passing one double stranded DNA duplex (transported helix) through a transient enzyme-bridged break in another (gated helix). This activity is re...

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Bibliographic Details
Main Authors: Caroline A. Austin, Ka C. Lee, Rebecca L. Swan, Mushtaq M. Khazeem, Catriona M. Manville, Peter Cridland, Achim Treumann, Andrew Porter, Nick J. Morris, Ian G. Cowell
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
Topoisomerase II
TOP2
Cell cycle
cell biology
transcription
review
Online Access:http://www.mdpi.com/1422-0067/19/9/2765

Internet

http://www.mdpi.com/1422-0067/19/9/2765

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