Adaption of FMDV Asia-1 to Suspension Culture: Cell Resistance Is Overcome by Virus Capsid Alterations

Foot-and-mouth disease virus (FMDV) causes a highly contagious disease with catastrophic economic impact for affected countries. BHK21 suspension cells are preferred for the industrial production of FMDV vaccine antigen, but not all virus strains can be successfully propagated in these cells. Seroty...

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Bibliographic Details
Main Authors: Veronika Dill, Bernd Hoffmann, Aline Zimmer, Martin Beer, Michael Eschbaumer
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/9/8/231