Electrophysiological Remodeling in Heart Failure Dyssynchrony vs. Resynchronization

The electrophysiological hallmark of cells and tissues isolated from failing hearts is prolongation of action potential duration (APD) and conduction slowing. In human studies and a number of animal models of heart failure, functional downregulation of K currents and alterations in depolarizing Na a...

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Bibliographic Details
Main Authors: Takeshi Aiba, MD PhD, Gordon F. Tomaselli, MD, Wataru Shimizu, MD PhD
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Arrhythmia
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1880427610800110