Transcriptional network constituted of CBP, Ku70, NOX2, and BAX prevents the cell death of necrosis, paraptosis, and apoptosis in human melanoma
Abstract CREB-binding protein (CBP) is an acetyltransferase known to play multiple roles in the transcriptions of genes involving oxidative metabolism, cell cycle, DNA damage checkpoints, and cell death. In this study, CBP was found to positively regulate the expression of Ku70, and both CBP and Ku7...
Main Authors: | Liang Ding, Yalei Wen, Xin Zhang, Fang Zhao, Kenao Lv, Jian-hong Shi, Shigang Shen, Xuefeng Pan |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-02-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00417-z |
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