Transcriptional network constituted of CBP, Ku70, NOX2, and BAX prevents the cell death of necrosis, paraptosis, and apoptosis in human melanoma

Abstract CREB-binding protein (CBP) is an acetyltransferase known to play multiple roles in the transcriptions of genes involving oxidative metabolism, cell cycle, DNA damage checkpoints, and cell death. In this study, CBP was found to positively regulate the expression of Ku70, and both CBP and Ku7...

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Bibliographic Details
Main Authors: Liang Ding, Yalei Wen, Xin Zhang, Fang Zhao, Kenao Lv, Jian-hong Shi, Shigang Shen, Xuefeng Pan
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00417-z