Delivery of Cell-Specific Aptamers to the Arterial Wall with an Occlusion Perfusion Catheter

Current strategies to prevent restenosis following endovascular treatment include the local delivery of anti-proliferative agents to inhibit vascular smooth muscle cell (VSMC) proliferation and migration. These agents, not specific to VSMCs, are deposited on the luminal surface and therefore target...

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Bibliographic Details
Main Authors: Ofonime Udofot, Li-Hsien Lin, William H. Thiel, Megan Erwin, Emily Turner, Francis J. Miller, Jr., Paloma H. Giangrande, Saami K. Yazdani
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253119300630