Toll-Like Receptor Transcriptome in the HPV-Positive Cervical Cancer Microenvironment

The human papillomavirus (HPV) directly infects cervical keratinocytes and interferes with TLR signalling. To shed light on the effect of HPV on upstream receptors, we evaluated TLRs 1–9 gene expression in HPV-negative normal and HPV-positive pre-malignant and malignant ex vivo cervical tissue. Quan...

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Bibliographic Details
Main Authors: Correne A. DeCarlo, Bruce Rosa, Robert Jackson, Sarah Niccoli, Nicholas G. Escott, Ingeborg Zehbe
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/785825