Novel Aβ peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease

<p>Abstract</p> <p>Background</p> <p>Alzheimer's disease, a common dementia of the elder, is characterized by accumulation of protein amyloid deposits in the brain. Immunization to prevent this accumulation has been proposed as a therapeutic possibility, although a...

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Bibliographic Details
Main Authors: Cribbs David H, Yazan Ozkan, Webster Scott D, Hernandez Irma, Kayed Rakez, Fonseca Maria I, Zhou Jun, Glabe Charles G, Tenner Andrea J
Format: Article
Language:English
Published: BMC 2005-12-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/2/1/28