RHBDL2 Is a Critical Membrane Protease for Anoikis Resistance in Human Malignant Epithelial Cells

Anoikis resistance allows metastatic tumor cells to survive in a homeless environment. Activation of epithelial growth factor receptor (EGFR) signaling is one of the key mechanisms for metastatic tumor cells to resist anoikis, yet the regulation mechanisms of homeless-triggered EGFR activation in me...

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Bibliographic Details
Main Authors: Tsung-Lin Cheng, Chao-Han Lai, Shinn-Jong Jiang, Jui-Hsiang Hung, Shi-Kai Liu, Bi-Ing Chang, Guey-Yueh Shi, Hua-Lin Wu
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/902987