Establishment of an in vitro culture system to study the developmental biology of Onchocerca volvulus with implications for anti-Onchocerca drug discovery and screening.

Establishment of an in vitro culture system to study the developmental biology of Onchocerca volvulus with implications for anti-Onchocerca drug discovery and screening.

<h4>Background</h4>Infections with Onchocerca volvulus nematodes remain a threat in Sub-Saharan Africa after three decades of ivermectin mass drug administration. Despite this effort, there is still an urgent need for understanding the parasite biology especially the mating behaviour and...

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Bibliographic Details
Main Authors: Narcisse V T Gandjui, Abdel J Njouendou, Eric N Gemeg, Fanny F Fombad, Manuel Ritter, Chi A Kien, Valerine C Chunda, Jerome Fru, Mathias E Esum, Marc P Hübner, Peter A Enyong, Achim Hoerauf, Samuel Wanji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008513

Internet

https://doi.org/10.1371/journal.pntd.0008513

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