Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the MK2 Inhibitor ATI-450 in Healthy Subjects: A Placebo-Controlled, Randomized Phase 1 Study

David Gordon,1 Edward T Hellriegel,1 Heidi Rath Hope,2 David Burt,1 Joseph B Monahan2 1Research and Development, Aclaris Therapeutics, Inc., Wayne, PA, USA; 2Research and Development, Aclaris Therapeutics, Inc., and Confluence Discovery Technologies, Inc., St. Louis, MO, USACorrespondence: David Gor...

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Bibliographic Details
Main Authors: Gordon D, Hellriegel ET, Hope HR, Burt D, Monahan JB
Format: Article
Language:English
Published: Dove Medical Press 2021-06-01
Series:Clinical Pharmacology : Advances and Applications
Subjects:
Online Access:https://www.dovepress.com/safety-tolerability-pharmacokinetics-and-pharmacodynamics-of-the-mk2-i-peer-reviewed-fulltext-article-CPAA