Gene-gene and gene-sex epistatic interactions of MiR146a, IRF5, IKZF1, ETS1 and IL21 in systemic lupus erythematosus.

Gene-gene and gene-sex epistatic interactions of MiR146a, IRF5, IKZF1, ETS1 and IL21 in systemic lupus erythematosus.

Several confirmed genetic susceptibility loci involved in the interferon signaling and Th17/B cell response for SLE in Chinese Han populations have been described. Available data also indicate that sex-specific genetic differences contribute to SLE susceptibility. The aim of this study was to test f...

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Bibliographic Details
Main Authors: Rui-Xue Leng, Wei Wang, Han Cen, Mo Zhou, Chen-Chen Feng, Yan Zhu, Xiao-Ke Yang, Mei Yang, Yu Zhai, Bao-Zhu Li, Xiao-Song Wang, Rui Li, Gui-Mei Chen, Hong Chen, Hai-Feng Pan, Dong-Qing Ye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3517573?pdf=render

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http://europepmc.org/articles/PMC3517573?pdf=render

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