Edgeworthia gardneri (Wall.) Meisn. Water Extract Ameliorates Palmitate Induced Insulin Resistance by Regulating IRS1/GSK3β/FoxO1 Signaling Pathway in Human HepG2 Hepatocytes

Edgeworthia gardneri (Wall.) Meisn. Water Extract Ameliorates Palmitate Induced Insulin Resistance by Regulating IRS1/GSK3β/FoxO1 Signaling Pathway in Human HepG2 Hepatocytes

The flower of Edgeworthia gardneri (Wall.) Meisn is commonly used in beverage products in Tibet and has potential health benefits for diabetes. However, the mechanisms underlying anti-insulin resistance (IR) action of the flower of E. gardneri are not fully understood. This study aims to investigate...

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Bibliographic Details
Main Authors: Yi Zhang, Li Shan Yan, Yu Ding, Brian Chi Yan Cheng, Gan Luo, Jing Kong, Tong Hua Liu, Shuo Feng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
Edgeworthia gardneri
insulin resistance
palmitate
IRS1/GSK3β/FoxO1 signaling pathway
HepG2 cells
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01666/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01666/full

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