Interleukin-32θ Triggers Cellular Senescence and Reduces Sensitivity to Doxorubicin-Mediated Cytotoxicity in MDA-MB-231 Cells

Interleukin-32θ Triggers Cellular Senescence and Reduces Sensitivity to Doxorubicin-Mediated Cytotoxicity in MDA-MB-231 Cells

The recently discovered interleukin (IL)- 32 isoform IL-32θ exerts anti-metastatic effects in the breast tumor microenvironment. However, the involvement of IL-32θ in breast cancer cell proliferation is not yet fully understood; therefore, the current study aimed to determine how IL-32θ affects canc...

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Bibliographic Details
Main Authors: Thu-Huyen Pham, Hyo-Min Park, Jinju Kim, Jin-Tae Hong, Do-Young Yoon
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
interleukin-32θ
breast cancer
senescence
cell cycle arrest
drug resistance
Online Access:https://www.mdpi.com/1422-0067/22/9/4974

Internet

https://www.mdpi.com/1422-0067/22/9/4974

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