Naldemedine is effective in the treatment of opioid-induced constipation in patients with chronic non-cancer pain who had a poor response to laxatives

Background: Two studies demonstrated the efficacy and safety of naldemedine in adult patients with chronic non-cancer pain and opioid-induced constipation (OIC). However, no studies have compared the efficacy of peripherally acting µ-opioid receptor antagonists in patients with adequate and inadequa...

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Bibliographic Details
Main Authors: Martin E. Hale, James E. Wild, Tadaaki Yamada, Takaaki Yokota, Jan Tack, Viola Andresen, Asbjørn Mohr Drewes
Format: Article
Language:English
Published: SAGE Publishing 2021-07-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/17562848211032320