Clinical Characterization of Mismatch Repair Gene-Deficient Metastatic Castration-Resistant Prostate Cancer

Clinical Characterization of Mismatch Repair Gene-Deficient Metastatic Castration-Resistant Prostate Cancer

Mismatch repair-deficient (dMMR) prostate cancer is rare and has not been well studied. We aimed to evaluate the clinical characterization of dMMR metastatic castration-resistant prostate cancer (mCRPC) patients. The MMR genes include MLH1, MLH3, MSH2, MSH6, PMS1, PMS2, and EPCAM, and were analyzed...

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Bibliographic Details
Main Authors:	Senlin Ye, Haohui Wang, Kancheng He, Mou Peng, Yinhuai Wang, Yuanwei Li, Shusuan Jiang, Jin Li, Lu Yi, Rongrong Cui
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-10-01
Series:	Frontiers in Oncology
Subjects:	mismatch repair deficiency castration-resistant prostate cancer next-generation sequencing cell-free DNA novel hormone therapy
Online Access:	https://www.frontiersin.org/article/10.3389/fonc.2020.533282/full

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