Clinical Characterization of Mismatch Repair Gene-Deficient Metastatic Castration-Resistant Prostate Cancer

Clinical Characterization of Mismatch Repair Gene-Deficient Metastatic Castration-Resistant Prostate Cancer

Mismatch repair-deficient (dMMR) prostate cancer is rare and has not been well studied. We aimed to evaluate the clinical characterization of dMMR metastatic castration-resistant prostate cancer (mCRPC) patients. The MMR genes include MLH1, MLH3, MSH2, MSH6, PMS1, PMS2, and EPCAM, and were analyzed...

Full description

Bibliographic Details
Main Authors: Senlin Ye, Haohui Wang, Kancheng He, Mou Peng, Yinhuai Wang, Yuanwei Li, Shusuan Jiang, Jin Li, Lu Yi, Rongrong Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
mismatch repair deficiency
castration-resistant prostate cancer
next-generation sequencing
cell-free DNA
novel hormone therapy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.533282/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.533282/full

Similar Items