Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti‐inflammation, anti‐apoptosis, and ERK activation

Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti‐inflammation, anti‐apoptosis, and ERK activation

ATP‐sensitive potassium channels (KATPs) have protective effects in ischemia–reperfusion‐induced injuries and can be activated by levosimendan. This study investigated the effects of levosimendan on renal injury, inflammation, apoptosis, and survival in a rat model of acute kidney injury (AKI) follo...

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Bibliographic Details
Main Authors: Lei Tian, Shiwei Wang, Li Zhao, Xiaoye Lu, Changqing Zhu, Hao Gong, Weiqiang Yang
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:FEBS Open Bio
Subjects:
acute kidney injury
cardiac arrest
cardiopulmonary resuscitation
ERK
levosimendan
Online Access:https://doi.org/10.1002/2211-5463.13227

Internet

https://doi.org/10.1002/2211-5463.13227

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