HIV gp120 Induces the Release of Proinflammatory, Angiogenic, and Lymphangiogenic Factors from Human Lung Mast Cells

Human lung mast cells (HLMCs) express the high-affinity receptor FcεRI for IgE and are involved in chronic pulmonary diseases occurring at high frequency among HIV-infected individuals. Immunoglobulin superantigens bind to the variable regions of either the heavy or light chain of immunoglobulins (I...

Full description

Bibliographic Details
Main Authors: Giancarlo Marone, Francesca Wanda Rossi, Antonio Pecoraro, Valentina Pucino, Gjada Criscuolo, Amato de Paulis, Giuseppe Spadaro, Gianni Marone, Gilda Varricchi
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Vaccines
Subjects:
HIV
IgE
Online Access:https://www.mdpi.com/2076-393X/8/2/208