Inhibition of Suicidal Erythrocyte Death by Volasertib

Inhibition of Suicidal Erythrocyte Death by Volasertib

Background/Aims: The Polo-like kinase 1 (Plk1) inhibitor volasertib is used in the treatment of malignancy. Volasertib is partially effective by triggering suicidal death or apoptosis of tumor cells. Similar to apoptosis of nucleated cells, erythrocytes may enter suicidal cell death or eryptosis, wh...

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Bibliographic Details
Main Authors: Abdulla Al Mamun Bhuyan, A.K.M. Ashiqul Haque, Itishri Sahu, Hang Cao, Michael S.D. Kormann, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Oxidative stress
Hyperosmotic shock
Ionomycin
Calcium
Volasertib
Phosphatidylserine
Eryptosis; energy depletion
Online Access:https://www.karger.com/Article/FullText/481969

Internet

https://www.karger.com/Article/FullText/481969

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