Antibiotics Attenuate Methamphetamine-Induced Hepatotoxicity by Regulating Oxidative Stress and TLR4/MyD88/Traf6 Axis

Antibiotics Attenuate Methamphetamine-Induced Hepatotoxicity by Regulating Oxidative Stress and TLR4/MyD88/Traf6 Axis

Methamphetamine (METH) is a major psychostimulant drug of abuse worldwide, and its neurotoxicity has been studied extensively. In addition to neurotoxicity, METH can also induce hepatotoxicity. The underlying mechanism of intestinal microorganisms in METH-induced hepatotoxicity remains unclear. In t...

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Bibliographic Details
Main Authors: Li-Jian Chen, Jie-Tao He, Ming Pan, Jia-Li Liu, Kai-Kai Zhang, Jia-Hao Li, Li-Bin Wang, Ling-Ling Xu, Yu-Kui Chen, Qin-Yao Zhang, Dong-Ri Li, Jing-Tao Xu, Xiao-Li Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
methamphetamine
antibiotics
hepatotoxicity
RNA-seq
RT-qPCR
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.716703/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.716703/full

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