Molecular networks of FOXP family: dual biologic functions, interplay with other molecules and clinical implications in cancer progression

Abstract Though Forkhead box P (FOXP) transcription factors comprising of FOXP1, FOXP2, FOXP3 and FOXP4 are involved in the embryonic development, immune disorders and cancer progression, the underlying function of FOXP3 targeting CD4 + CD25+ regulatory T (Treg) cells and the dual roles of FOXP prot...

Full description

Bibliographic Details
Main Authors: Ju-Ha Kim, Jisung Hwang, Ji Hoon Jung, Hyo-Jung Lee, Dae Young Lee, Sung-Hoon Kim
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-019-1110-3