Assessing the accuracy and power of population genetic inference from low-pass next-generation sequencing data

Next-generation sequencing technologies have made it possible to address principle population genetic questions in almost any system, but high error rates associated with this data can introduce significant biases into downstream analyses, so careful consideration of experimental design and interpre...

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Bibliographic Details
Main Authors: Jacob Evan Crawford, Brian P Lazzaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00066/full