A comprehensive DNA panel next generation sequencing approach supporting diagnostics and therapy prediction in neurooncology

A comprehensive DNA panel next generation sequencing approach supporting diagnostics and therapy prediction in neurooncology

Abstract Recent updates in the classification of central nervous system (CNS) tumors have increased the need for molecular testing. Assessment of multiple alterations in parallel, complex combinations of gene sequence and chromosomal changes, as well as therapy prediction by identification of action...

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Bibliographic Details
Main Authors: Julia Lorenz, Tanja Rothhammer-Hampl, Saida Zoubaa, Elisabeth Bumes, Tobias Pukrop, Oliver Kölbl, Selim Corbacioglu, Nils O. Schmidt, Martin Proescholdt, Peter Hau, Markus J. Riemenschneider
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Acta Neuropathologica Communications
Subjects:
Glioblastoma
Glioma
Meningioma
Medulloblastoma
Next generation sequencing
Targeted therapy
Online Access:http://link.springer.com/article/10.1186/s40478-020-01000-w

Internet

http://link.springer.com/article/10.1186/s40478-020-01000-w

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