In Situ Staining and Laser Capture Microdissection of Lymph Node Residing SIV Gag-Specific CD8+ T cells--A Tool to Interrogate a Functional Immune Response Ex Vivo.

In Situ Staining and Laser Capture Microdissection of Lymph Node Residing SIV Gag-Specific CD8+ T cells--A Tool to Interrogate a Functional Immune Response Ex Vivo.

While a plethora of data describes the essential role of systemic CD8+ T cells in the control of SIV replication little is known about the local in situ CD8+ T cell immune responses against SIV at the intact tissue level, due to technical limitations. In situ staining, using GagCM9 Qdot 655 multimer...

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Bibliographic Details
Main Authors: Annelie Tjernlund, Adam Burgener, Jessica M Lindvall, Tao Peng, Jia Zhu, Lars Öhrmalm, Louis J Picker, Kristina Broliden, M Juliana McElrath, Lawrence Corey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4795610?pdf=render

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http://europepmc.org/articles/PMC4795610?pdf=render

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