Clinical Use of the Self-Assembling Peptide RADA16: A Review of Current and Future Trends in Biomedicine

Clinical Use of the Self-Assembling Peptide RADA16: A Review of Current and Future Trends in Biomedicine

RADA16 is a synthetic peptide that exists as a viscous solution in an acidic formulation. In an acidic aqueous environment, the peptides spontaneously self-assemble into β-sheet nanofibers. Upon exposure and buffering of RADA16 solution to the physiological pH of biological fluids such as blood, int...

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Bibliographic Details
Main Authors: Sharanya Sankar, Kate O’Neill, Maurice Bagot D’Arc, Florian Rebeca, Marie Buffier, Elton Aleksi, Melanie Fan, Noriaki Matsuda, Eun Seok Gil, Lisa Spirio
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
self-assembling peptide hydrogel
nanofiber
RADA16
hemostasis
tissue regeneration
wound healing
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.679525/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2021.679525/full

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