Overexpression of miR-223 Promotes Tolerogenic Properties of Dendritic Cells Involved in Heart Transplantation Tolerance by Targeting Irak1

Overexpression of miR-223 Promotes Tolerogenic Properties of Dendritic Cells Involved in Heart Transplantation Tolerance by Targeting Irak1

Dendritic cells (DCs) are key mediators of transplant rejection. Numerous factors have been identified that regulate transplant immunopathology by modulating the function of DCs. Among these, microRNAs (miRNAs), small non-coding RNA molecules, have received much attention. The miRNA miR-223 is very...

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Bibliographic Details
Main Authors: Shun Yuan, Yuanyang Chen, Min Zhang, Zhiwei Wang, Zhipeng Hu, Yongle Ruan, Zongli Ren, Feng Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
miR-223
dendritic cells
Irak1
heart transplantation
immunosuppression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.676337/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.676337/full

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