The cellular functions of RASSF1A and its inactivation in prostate cancer

Epigenetic events significantly impact the transcriptome of cells and often contribute to the onset and progression of human cancers. RASSF1A (Ras-association domain family 1 isoform A), a well-known tumor suppressor gene, is frequently silenced by epigenetic mechanisms such as promoter hypermethyla...

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Bibliographic Details
Main Authors: Karishma S Amin, Partha P Banerjee
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Carcinogenesis
Subjects:
Online Access:http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2012;volume=11;issue=1;spage=3;epage=3;aulast=Amin