FTO Knockout Causes Chromosome Instability and G2/M Arrest in Mouse GC-1 Cells

FTO Knockout Causes Chromosome Instability and G2/M Arrest in Mouse GC-1 Cells

N6-methyladenosine (m6A) is the most abundant modification on eukaryotic mRNA. m6A plays important roles in the regulation of post-transcriptional RNA splicing, translation, and degradation. Increasing studies have uncovered the significance of m6A in various biological processes such as stem cell f...

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Bibliographic Details
Main Authors: Tao Huang, Qiang Gao, Tongying Feng, Yi Zheng, Jiayin Guo, Wenxian Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Genetics
Subjects:
N6-methyladenosine
FTO
spermatogonia
cell cycle
chromosome instability
mitotic checkpoint
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00732/full

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https://www.frontiersin.org/article/10.3389/fgene.2018.00732/full

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