Antiproliferative and Apoptotic Activity of Chamaecyparis obtusa Leaf Extract against the HCT116 Human Colorectal Cancer Cell Line and Investigation of the Bioactive Compound by Gas Chromatography-Mass Spectrometry-Based Metabolomics

Antiproliferative and Apoptotic Activity of Chamaecyparis obtusa Leaf Extract against the HCT116 Human Colorectal Cancer Cell Line and Investigation of the Bioactive Compound by Gas Chromatography-Mass Spectrometry-Based Metabolomics

Chamaecyparis obtusa (CO) belongs to the Cupressaceae family, and it is found widely distributed in Japan and Korea. In this study, the anti-proliferative activities of the methanol and water extracts of CO leaves against a human colorectal cancer cell line (HCT116) were investigated. The methanol e...

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Bibliographic Details
Main Authors: Hye-Youn Kim, Seul-Gi Lee, Taek-Joo Oh, Sa Rang Lim, So-Hyun Kim, Hong Jin Lee, Young-Suk Kim, Hyung-Kyoon Choi
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Molecules
Subjects:
Chamaecyparis obtusa
human colorectal cancer
metabolite profiling
gas chromatography-mass spectrometry
anthricin
Online Access:http://www.mdpi.com/1420-3049/20/10/18066

Internet

http://www.mdpi.com/1420-3049/20/10/18066

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