Antiviral effect of high-dose ivermectin in adults with COVID-19: A proof-of-concept randomized trial

Antiviral effect of high-dose ivermectin in adults with COVID-19: A proof-of-concept randomized trial

Background: There are limited antiviral options for the treatment of patients with COVID-19. Ivermectin (IVM), a macrocyclic lactone with a wide anti-parasitary spectrum, has shown potent activity against SARS-CoV-2 in vitro. This study aimed at assessing the antiviral effect of IVM on viral load of...

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Bibliographic Details
Main Authors: Alejandro Krolewiecki, Adrián Lifschitz, Matías Moragas, Marina Travacio, Ricardo Valentini, Daniel F. Alonso, Rubén Solari, Marcelo A. Tinelli, Rubén O. Cimino, Luis Álvarez, Pedro E. Fleitas, Laura Ceballos, Marcelo Golemba, Florencia Fernández, Diego Fernández de Oliveira, German Astudillo, Inés Baeck, Javier Farina, Georgina A. Cardama, Andrea Mangano, Eduardo Spitzer, Silvia Gold, Carlos Lanusse
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:EClinicalMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S258953702100239X

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http://www.sciencedirect.com/science/article/pii/S258953702100239X

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