A Simple Method to Detect the Inhibition of Transcription Factor-DNA Binding Due to Protein–Protein Interactions In Vivo

A Simple Method to Detect the Inhibition of Transcription Factor-DNA Binding Due to Protein–Protein Interactions In Vivo

Binding of transcription factors (TFs) to <i>cis</i>-regulatory elements (DNA) could modulate the expression of downstream genes, while interactions between TFs and other proteins might inhibit them binding to DNA. Nowadays, electrophoretic mobility shift assay (EMSA) and chromatin immun...

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Bibliographic Details
Main Authors: Guangzhe Yang, Dong Chao, Zhenhua Ming, Jixing Xia
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Genes
Subjects:
protein–DNA binding
protein–protein interactions
yeast one-hybrid
EMSA
ChIP
Online Access:https://www.mdpi.com/2073-4425/10/9/684

Internet

https://www.mdpi.com/2073-4425/10/9/684

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