Crystal structure of Legionella DotD: insights into the relationship between type IVB and type II/III secretion systems.
The Dot/Icm type IVB secretion system (T4BSS) is a pivotal determinant of Legionella pneumophila pathogenesis. L. pneumophila translocate more than 100 effector proteins into host cytoplasm using Dot/Icm T4BSS, modulating host cellular functions to establish a replicative niche within host cells. Th...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-10-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2951367?pdf=render |