Crystal structure of Legionella DotD: insights into the relationship between type IVB and type II/III secretion systems.

The Dot/Icm type IVB secretion system (T4BSS) is a pivotal determinant of Legionella pneumophila pathogenesis. L. pneumophila translocate more than 100 effector proteins into host cytoplasm using Dot/Icm T4BSS, modulating host cellular functions to establish a replicative niche within host cells. Th...

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Bibliographic Details
Main Authors: Noboru Nakano, Tomoko Kubori, Miki Kinoshita, Katsumi Imada, Hiroki Nagai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2951367?pdf=render