Virus-like particles of SARS-like coronavirus formed by membrane proteins from different origins demonstrate stimulating activity in human dendritic cells.

The pathogenesis of SARS coronavirus (CoV) remains poorly understood. In the current study, two recombinant baculovirus were generated to express the spike (S) protein of SARS-like coronavirus (SL-CoV) isolated from bats (vAcBS) and the envelope (E) and membrane (M) proteins of SARS-CoV, respectivel...

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Bibliographic Details
Main Authors: Bingke Bai, Qinxue Hu, Hui Hu, Peng Zhou, Zhengli Shi, Jin Meng, Baojing Lu, Yi Huang, Panyong Mao, Hanzhong Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2441860?pdf=render