Altered neuronal firing pattern of the basal ganglia nucleus plays a role in levodopa-induced dyskinesia in patients with Parkinson's disease

Background: Levodopa therapy alleviates the symptoms of Parkinson's disease (PD), but long-term treatment often leads to motor complications such as levodopa-induced dyskinesia (LID). Aim: To explore the neuronal activity in the basal ganglia nuclei in patients with PD and LID. Methods: Thirty...

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Bibliographic Details
Main Authors: Xiaoyu eLi, Ping eZhuang, Yongjie eLi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Human Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00630/full