Regression analysis for constraining free parameters in electrophysiological models of cardiac cells.
A major challenge in computational biology is constraining free parameters in mathematical models. Adjusting a parameter to make a given model output more realistic sometimes has unexpected and undesirable effects on other model behaviors. Here, we extend a regression-based method for parameter sens...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-09-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2932676?pdf=render |