DNA–protein cross-link repair: what do we know now?
Abstract When a protein is covalently and irreversibly bound to DNA (i.e., a DNA–protein cross-link [DPC]), it may obstruct any DNA-based transaction, such as transcription and replication. DPC formation is very common in cells, as it can arise from endogenous factors, such as aldehyde produced duri...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | Cell & Bioscience |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13578-019-0366-z |