Correlated metabolomic, genomic, and histologic phenotypes in histologically normal breast tissue.

Breast carcinogenesis is a multistep process accompanied by widespread molecular and genomic alterations, both in tumor and in surrounding microenvironment. It is known that tumors have altered metabolism, but the metabolic changes in normal or cancer-adjacent, nonmalignant normal tissues and how th...

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Bibliographic Details
Main Authors: Xuezheng Sun, Delisha A Stewart, Rupninder Sandhu, Erin L Kirk, Wimal W Pathmasiri, Susan L McRitchie, Robert F Clark, Melissa A Troester, Susan J Sumner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5905995?pdf=render